'Population based surveillance of seasonal Influenza in rural population of Western India [Pune district]'. Over 500 nasal and oropharyngial samples of secretions from people suffering from mild to severe influenza will be collected per year for three years. Study aims at looking at the incidence, severity of cases and the strains of virus involved. To increase the sensitivity of surveillance system co-operation from private practitioners as well as pharmacists will be sought. Sponsors: CDC Atlanta.

'Influenza Disease Burden in India (IDBI)' study:

Population based surveillance of severe Influenza in rural populations of Western India [VRHP, Pune], North India [Ballabhgarh, AIIMS], Southern India [CMC Vellore]. Involves a sensitive system to catch incidence of severe influenza in the study area. Surveillance at two levels: Hospital based- to catch severe admitted cases and household survey- to catch missed hospitalizations and non-medical care seeking patients. Involves demographic surveillance, risk factor surveillance and death surveys. Disease burden estimation will be done for medical burden and direct and indirect economic costs to the society. Surveillance of H1N1 influenza and study of evolution of epidemic in the study area will be included soon. Understanding of influenza Seasonality in the area will be bolstered with the help of weather stations set up in the area by one of our collaborators- Chest Research Foundation [CRF]. A comprehensive study to asses burden of disease on rural populations.

For the first time at VRHP data collection will be done by EDC [electronic data capture] method. The data entry software, synchronization and database creation was done indigenously by Mr. Prasad Joshi and Mr. Neeraj Kashyap- our data management team. It will be an exemplary activity where field workers [Field Research Assistants] will collect data using mini laptops.

With the novel H1N1 epidemic spreading fast from Pune city [which is the epicentre of 'Swine' outbreak in India] which is just 30 kms away, they team is in a unique position to carry out outbreak investigation and study transmission dynamics of the spread.

Innovation suggested by Vadu team have resulted in incorporation of data collected through Weather stations to be considered for better understanding of seasonality in the area. 30 percent co-infection rates with Malaria observed in the area is a finding interesting to many scientists and epidemiologists.

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